A study on dosimetry accuracy of Strut-Adjust Volume Implant (SAVI) brachytherapy
نویسندگان
چکیده مقاله:
Introduction: Accelerated Partial Breast Irradiation (APBI) is an effective treatment for breast carcinomas because of its limited number of fractions. Strut-adjusted volume implant (SAVI) is a HDR brachytherapy applicator to deliver the prescription dose with good PTV coverage and acceptable dose to skin, chest wall and organ at risks. Acceptable clinical outcomes depend on accurate dosimetry methods. Currently water is used as the reference dosimetry phantom material in treatment planning systems. The purpose of this study is to consider the corrections on phantom material and geometry in dose distribution of SAVI brachytherapy simulation using MCNP5 Monte Carlo code. Materials and Methods: SAVI with 8 peripheral source channels were considered expanded inside the lumpectomy cavity in breast. Three realistic phantoms were employed to perform the step by step corrections and dose distributions were compared with that of water. Considerations were included using the ICRU-44 defined breast material as the real breast composition and moreover the air-tissue interferences at the skin, lung and the air cavity inside the SAVI were studied. Results: According to the results, the dose differences due to the breast material corrections were less than 1% in the most points of breast and only 2-3% overestimation were observed close to the skin. Breast phantoms containing air cavity have shown up to 2% decreases in regions around it. Finally a phantom with both noted corrections and a curved surface for breast skin, corrected the calculations with about 3-5% underestimations at skin. Conclusion: According to the results of this study, dose distributions in breast phantoms containing different materials does not differ significantly with the dose distribution in water phantom. Conservative approximations can be provided with water phantom and it doesn’t seem necessary that the current treatment planning systems be replaced with the model-based patient specific dosimetry methods.
منابع مشابه
Dosimetric performance of Strut-Adjusted Volume Implant: a new single-entry multicatheter breast brachytherapy applicator.
PURPOSE To evaluate the dosimetric performance and clinical utility of the Strut-Adjusted Volume Implant (SAVI) (Cianna Medical, Aliso Viejo, CA) applicator when used as the sole method of radiation therapy for patients with early breast carcinoma. METHODS AND MATERIALS The dosimetric performance of a Phase II clinical trial has been reported using the SAVI applicator for patients with early ...
متن کاملDosimetrical Evaluation and Clinical Implementation of a Strut-adjusted-volume-implant Savi Device Used for Accelerated Partial Breast Irradiation
The SAVI (the Strut Adjusted Volume Implant) device is one of the most novel devices used in Accelerated Partial Breast Irradiation (APBI). Various dosimetric parameters, as well as doses to adjacent critical structures, have been evaluated in 121 patients in this single institution 5-year retrospective study, using dose volume histogram (DVHs): Coverage Index (CI), cavity and planning target v...
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عنوان ژورنال
دوره 15 شماره Special Issue-12th. Iranian Congress of Medical Physics
صفحات 154- 154
تاریخ انتشار 2018-12-01
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